Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes-Reference-Cited by-同舟云学术

Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes

Published:2017-01-06 Issue:4 Volume:60 Page:656-667
ISSN:0012-186X
Container-title:Diabetologia
language:en
Short-container-title:Diabetologia

Author:

Marroqui Laura,Dos Santos Reinaldo S.,Op de beeck Anne,Coomans de Brachène Alexandra,Marselli Lorella,Marchetti Piero,Eizirik Decio L.

Funder

Innovative Medicines Initiative 2 Joint Undertaking

Horizon 2020 Program

Fonds National de la Recherche Scientifique, Belgium

NIH-NIDDK-HIRN Consortium

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00125-016-4201-3.pdf

Reference44 articles.

1. Richardson SJ, Rodriguez-Calvo T, Gerling IC et al (2016) Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes. Diabetologia 59:2448–2458

2. Richardson SJ, Morgan NG, Foulis AK (2014) Pancreatic pathology in type 1 diabetes mellitus. Endocr Pathol 25:80–92

3. Marhfour I, Lopez XM, Lefkaditis D et al (2012) Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes. Diabetologia 55:2417–2420

4. Tersey SA, Nishiki Y, Templin AT et al (2012) Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes 61:818–827

5. Engin F, Yermalovich A, Nguyen T et al (2013) Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes. Sci Transl Med 5:211ra156

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