Fatty acid desaturases in human adipose tissue: relationships between gene expression, desaturation indexes and insulin resistance

Author:

Sjögren P.,Sierra-Johnson J.,Gertow K.,Rosell M.,Vessby B.,de Faire U.,Hamsten A.,Hellenius M.-L.,Fisher R. M.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference29 articles.

1. Food and Agriculture Organization/World Health Organization (2003) Recommendations for preventing type 2 diabetes. In: Diet, nutrition and the prevention of chronic diseases. Report of a joint WHO/FAO expert consultation. WHO technical report series 196. WHO, Geneva, pp 72–80. Available from http://www.who.int/entity/dietphysicalactivity/publications/trs916/en/gsfao_diabetes.pdf , accessed 26 October 2007

2. Nakamura MT, Nara TY (2004) Structure, function, and dietary regulation of Δ6, Δ5, and Δ9 desaturases. Annu Rev Nutr 24:345–376

3. Das UN (2005) A defect in the activity of Δ6 and Δ5 desaturases may be a factor predisposing to the development of insulin resistance syndrome. Prostaglandins Leukot Essent Fatty Acids 72:343–350

4. Ntambi JM, Miyazaki M (2004) Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res 43:91–104

5. Vessby B (2003) Dietary fat, fatty acid composition in plasma and the metabolic syndrome. Curr Opin Lipidol 14:15–19

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