Development of a multidimensional online method for the characterization and quantification of monoclonal antibodies using immobilized flow-through enzyme reactors
Author:
Funder
Federal Ministry for Economic Affairs and Energy
Publisher
Springer Science and Business Media LLC
Subject
Biochemistry,Analytical Chemistry
Link
https://link.springer.com/content/pdf/10.1007/s00216-021-03683-z.pdf
Reference27 articles.
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2. Shukla AA, Thommes J. Recent advances in large-scale production of monoclonal antibodies and related proteins. Trends Biotechnol. 2010;28(5):253–61. https://doi.org/10.1016/j.tibtech.2010.02.001.
3. Beck A, Sanglier-Cianferani S, Van Dorsselaer A. Biosimilar, biobetter, and next generation antibody characterization by mass spectrometry. Anal Chem. 2012;84(11):4637–46. https://doi.org/10.1021/ac3002885.
4. Ma J, Zhang L, Liang Z, Zhang W, Zhang Y. Monolith-based immobilized enzyme reactors: recent developments and applications for proteome analysis. J Sep Sci. 2007;30(17):3050–9. https://doi.org/10.1002/jssc.200700362.
5. Slechtova T, Gilar M, Kalikova K, Moore SM, Jorgenson JW, Tesarova E. Performance comparison of three trypsin columns used in liquid chromatography. J Chromatogr A. 2017;1490:126–32. https://doi.org/10.1016/j.chroma.2017.02.024.
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