Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry-Reference-Cited by-同舟云学术

Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry

Published:2023-01-20 Issue:4 Volume:95 Page:2203-2212
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Kuhne Felix¹²,Heinrich Katrin¹,Winter Martin¹,Fichtl Jürgen¹,Hoffmann Gabriel³,Zähringer Franziska³,Spitzauer Katharina¹,Meier Monika¹,Khan Tarik A.³,Bonnington Lea¹,Wagner Katharina¹,Stracke Jan Olaf³,Reusch Dietmar¹,Wegele Harald¹,Mormann Michael²,Bulau Patrick³^ORCID

Affiliation:

1. Pharma Technical Development, Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany

2. Institute of Hygiene, University of Münster, Robert-Koch-Strasse 41, 48149 Münster, Germany

3. Pharma Technical Development, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c03099

Reference48 articles.

1. Antibodies to watch in 2021

2. Antibodies to watch in 2022

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4. Recombinant antibody mixtures: Production strategies and cost considerations

5. The benefits of immunotherapy combinations

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