A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim-Reference-Cited by-同舟云学术

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A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim

Published:2017-12-12 Issue:2 Volume:45 Page:235-257
ISSN:1567-567X
Container-title:Journal of Pharmacokinetics and Pharmacodynamics
language:en
Short-container-title:J Pharmacokinet Pharmacodyn

Author:

Niederalt Christoph,Kuepfer Lars,Solodenko Juri,Eissing Thomas,Siegmund Hans-Ulrich,Block Michael,Willmann Stefan,Lippert Jörg

Funder

German Federal Ministry of Education and Research

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Link

http://link.springer.com/article/10.1007/s10928-017-9559-4/fulltext.html

Reference100 articles.

1. Edginton AN, Theil FP, Schmitt W, Willmann S (2008) Whole body physiologically-based pharmacokinetic models: their use in clinical drug development. Expert Opin Drug Metab Toxicol 4(9):1143–1152. https://doi.org/10.1517/17425255.4.9.1143

2. Jones HM, Chen Y, Gibson C, Heimbach T, Parrott N, Peters SA, Snoeys J, Upreti VV, Zheng M, Hall SD (2015) Physiologically based pharmacokinetic modeling in drug discovery and development: a pharmaceutical industry perspective. Clin Pharmacol Ther 97(3):247–262. https://doi.org/10.1002/cpt.37

3. Kuepfer L, Niederalt C, Wendl T, Schlender JF, Willmann S, Lippert J, Snoeys J, Block M, Eissing T, Teutonico D (2016) Applied concepts in PBPK modeling: how to build a PBPK/PD model. CPT Pharmacomet Syst Pharmacol 5(10):516–531. https://doi.org/10.1002/psp4.12134

4. Nestorov I (2003) Whole body pharmacokinetic models. Clin Pharmacokinet 42(10):883–908. https://doi.org/10.2165/00003088-200342100-00002

5. Nestorov I (2007) Whole-body physiologically based pharmacokinetic models. Expert Opin Drug Metab Toxicol 3(2):235–249. https://doi.org/10.1517/17425255.3.2.235

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