A pharmacokinetic binding model for bevacizumab and VEGF165 in colorectal cancer patients

Author:

Panoilia Eirini,Schindler Emilie,Samantas Epaminontas,Aravantinos Gerasimos,Kalofonos Haralabos P.,Christodoulou Christos,Patrinos George P.,Friberg Lena E.,Sivolapenko Gregory

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference52 articles.

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2. Final Labeling Text, BLA 125085 (2013) Center for Drug Evaluation and Research. U.S. Food and Drug Administration. http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/125085s285lbl.pdf . Accessed 20 Aug 2014

3. Avastin® (2014) Genentech USA, Inc. http://www.avastin.com/patient?cid=gne_WE_00000083 . Accessed 20 Aug 2014

4. Parikh SS, Mehta HH, Desai BI (2012) Advances in development of bevacizumab, a humanized antiangiogenic therapeutic monoclonal antibody targeting VEGF in cancer cells. Int J Pharm Biomed Sci 3:155–163

5. Tabrizi M, Roskos LK (2006) Exposure–response relationships for therapeutic biologic products. In: Meibohm B (ed) Pharmacokinetics and pharmacodynamics of biotech drugs. Principles and case studies in drug development. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, pp 295–327

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