Patulin activates the NRF2 pathway by modulation of miR-144 expression in HEK293 cells
Author:
Funder
National Research Foundation
Inyuvesi Yakwazulu-Natali
Publisher
Springer Science and Business Media LLC
Subject
Toxicology,Microbiology,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s12550-020-00418-4.pdf
Reference40 articles.
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2. Boonzaaijer G, Bobeldijk I, Van Osenbruggen W (2005) Analysis of patulin in Dutch food, an evaluation of a SPE based method. Food Control 16:587–591. https://doi.org/10.1016/j.foodcont.2004.06.020
3. Boussabbeh M, Ben Salem I, Prola A, Guilbert A, Bacha H, Abid-Essefi S, Lemaire C (2015) Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway. Toxicol Sci 144:328–337. https://doi.org/10.1093/toxsci/kfu319
4. Bryan HK, Olayanju A, Goldring CE, Park BK (2013) The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation. Biochem Pharmacol 85:705–717. https://doi.org/10.1016/j.bcp.2012.11.016
5. de Melo FT, de Oliveira IM, Greggio S, Dacosta JC, Guecheva TN, Saffi J, Henriques JA, Rosa RM (2012) DNA damage in organs of mice treated acutely with patulin, a known mycotoxin. Food Chem Toxicol 50(10):3548–3555. https://doi.org/10.1016/j.fct.2011.12.022
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