Rational design of stapled helical peptides as antidiabetic PPARγ antagonists to target coactivator site by decreasing unfavorable entropy penalty instead of increasing favorable enthalpy contribution
Author:
Funder
the AHWMU funds
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Biophysics
Link
https://link.springer.com/content/pdf/10.1007/s00249-022-01616-x.pdf
Reference44 articles.
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5. Casimiro-Garcia A, Heemstra RJ, Bigge CF, Chen J, Ciske FA, Davis JA, Ellis T, Esmaeil N, Flynn D, Han S, Jalaie M, Ohren JF, Powell NA (2013) Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ. Bioorg Med Chem Lett 23:767–772
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