Supercomputer Search for Coagulation Factor XIIa Inhibitors in the Chinese National Compound Library
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Publisher
Springer Nature Switzerland
Link
https://link.springer.com/content/pdf/10.1007/978-3-031-49432-1_19
Reference29 articles.
1. Macfarlane, R.G.: An enzyme cascade in theblood clotting mechanism, and its function as a biochemical amplifier. Nature 202, 498–499 (1964). https://doi.org/10.1038/202498a0
2. Tashchilova, A., et al.: New blood coagulation factor XIIa inhibitors: molecular modeling, synthesis, and experimental confirmation. Molecules 27(4), 1–18 (2022). https://doi.org/10.3390/molecules27041234
3. Hagedorn, I., et al.: Factor XIIa inhibitor recombinant human albumin infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding. Circulation 121(13), 1510–1517 (2010). https://doi.org/10.1161/CIRCULATIONAHA.109.924761
4. Matafonov, A., et al.: Factor XII inhibition reduces thrombus formation in a primate thrombosis model. Blood 123(11), 1739–1746 (2014). https://doi.org/10.1182/blood-2013-04-499111
5. Larsson, M., et al.: A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk. Sci. Transl. Med. 6(222), 222ra17 (2014). https://doi.org/10.1126/scitranslmed.3006804
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