Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Drug Discovery,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s12272-015-0618-3.pdf
Reference101 articles.
1. Aghajan, M., N. Jonai, K. Flick, F. Fu, M. Luo, X. Cai, I. Ouni, N. Pierce, X. Tang, B. Lomenick, R. Damoiseaux, R. Hao, P.M. Del Moral, R. Verma, Y. Li, C. Li, K.N. Houk, M.E. Jung, N. Zheng, L. Huang, R.J. Deshaies, P. Kaiser, and J. Huang. 2010. Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nature Biotechnology 28: 738–742.
2. Aoki, S., K. Morohashi, T. Sunoki, K. Kuramochi, S. Kobayashi, and F. Sugawara. 2007. Screening of paclitaxel-binding molecules from a library of random peptides displayed on T7 phage particles using paclitaxel-photoimmobilized resin. Bioconjugate Chemistry 18: 1981–1986.
3. Apsel, B., J.A. Blair, B. Gonzalez, T.M. Nazif, M.E. Feldman, B. Aizenstein, R. Hoffman, R.L. Williams, K.M. Shokat, and Z.A. Knight. 2008. Targeted polypharmacology: Discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nature Chemical Biology 4: 691–699.
4. Armour, C.D., and P.Y. Lum. 2005. From drug to protein: Using yeast genetics for high-throughput target discovery. Current Opinion in Chemical Biology 9: 20–24.
5. Bantscheff, M., D. Eberhard, Y. Abraham, S. Bastuck, M. Boesche, S. Hobson, T. Mathieson, J. Perrin, M. Raida, C. Rau, V. Reader, G. Sweetman, A. Bauer, T. Bouwmeester, C. Hopf, U. Kruse, G. Neubauer, N. Ramsden, J. Rick, B. Kuster, and G. Drewes. 2007. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nature Biotechnology 25: 1035–1044.
Cited by 43 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. 2,5-Dihydroxyterephthalic Acid: A Matrix for Improved Detection and Imaging of Amino Acids;Analytical Chemistry;2023-11-29
2. Identification of inhibitors for the transmembrane Trypanosoma cruzi eIF2α kinase relevant for parasite proliferation;Journal of Biological Chemistry;2023-07
3. Vutiglabridin Modulates Paraoxonase 1 and Ameliorates Diet-Induced Obesity in Hyperlipidemic Mice;Biomolecules;2023-04-18
4. Target Identification Approaches in Drug Discovery;Drug Target Selection and Validation;2022
5. Drug Discovery Paradigms: Phenotypic-Based Drug Discovery;Drug Target Selection and Validation;2022
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3