Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension-Reference-Cited by-同舟云学术

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Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

Published:2011-08 Issue:8 Volume:89 Page:771-783
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Sutendra Gopinath,Dromparis Peter,Bonnet Sébastien,Haromy Alois,McMurtry Michael S.,Bleackley R. Chris,Michelakis Evangelos D.

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00109-011-0762-2.pdf

Reference36 articles.

1. Dromparis P, Sutendra G, Michelakis ED (2010) The role of mitochondria in pulmonary vascular remodeling. J Mol Med 88:1003–1010

2. McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED (2004) Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res 95:830–840

3. Michelakis ED, Sutendra G, Dromparis P, Webster L, Haromy A, Niven E, Maguire C, Gammer TL, Mackey JR, Fulton D et al (2010) Metabolic modulation of glioblastoma with dichloroacetate. Sci Transl Med 2:31ra34

4. Sutendra G, Bonnet S, Rochefort G, Haromy A, Folmes KD, Lopaschuck GD, Dyck JRB, Michelakis ED (2010) Fatty acid oxidation and malonyl-CoA decarboxylase in vascular remodeling of pulmonary hypertension. Sci Transl Med 2:44ra58

5. Kim JW, Dang CV (2005) Multifaceted roles of glycolytic enzymes. Trends Biochem Sci 30:142–150

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