Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats

Author:

Bae Jin-Sook,Lee Jung Dae,Song Si-Whan,Shin Ho-Chul,Choi Yong-Kyu,Shin Chan Young,Lee Byung-Mu,Kim Kyu-BongORCID

Funder

Ministry of Food and Drug Safety

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference44 articles.

1. Aarflot RL (2013) Human exposures to parabens in cosmetics—a literature study. Faculty of Health Sciences/Department of Community Medicine

2. Ana F, Paula FA (2016) parabens paradoxes in cosmetic formulations: a review. Int J Pharm Sci Res 6:1–21

3. Anderson JM, Rodriguez A, Chang DT (2008) Foreign body reaction to biomaterials. Semin Immunol 20:86–100

4. Aubert N (2009) Blood plasma pharmacokinetics and mass balance of yotal radioactivity in Sprague-Dawley rats following single administration of three different parabens (methyl-, butyl-, propyl-) by three different routes of administration (oral, dermal, sub-cutaneous). CIT, Centre International de Toxicologie, Evreux, France. Study No. 34851 PAR 26

5. Aubert N, Ameller T, Legrand JJ (2012) Systemic exposure to parabens: pharmacokinetics, tissue distribution, excretion balance and plasma metabolites of [14C]-methyl-, propyl- and butylparaben in rats after oral, topical or subcutaneous administration. Food Chem Toxicol 50:445–454

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