Systemic exposure to parabens: Pharmacokinetics, tissue distribution, excretion balance and plasma metabolites of [14C]-methyl-, propyl- and butylparaben in rats after oral, topical or subcutaneous administration

Author:

Aubert Nicolas,Ameller Thibault,Legrand Jean-Jacques

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference48 articles.

1. Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronotreansferases in man;Abbas;Drug Metab. Pharmacokinet.,2010

2. Effects of skin metabolism on percutaneous penetration of lipophilic drugs;Bando;J. Pharm. Sci.,1997

3. BfR. Bundesamt für Risikobewertung, 2004. Paraben-haltige Deodorants und die Entstehung von Brustkrebs. Stellungnahme des BfR vom 13. February 2004. Available from: .

4. BfR. Bundesamt für Risikobewertung, 2011. Joint DE-UK position paper. Regulatory definition of an endocrine disrupter in relation to potential threat to human health. Berlin, Germany, 16 May, 2011. Available from: .

5. Parabens: a review of epidemiology, structure, allergenicity and hormonal properties;Cashman;Dermatitis,2005

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