1. Randy W,Schekman 美国 University of California-Berkeley 2014美国医学院院士;1992美国科学院院士;2002拉斯克奖 ;2013诺贝尔生理学或医学奖 Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers
2. Franz-Ulrich,Hartl 德国 Max Planck Society 2011拉斯克奖;2011美国科学院院士 Multiple pathways of toxicity induced by c9orf72 dipeptide repeat aggregates and G(4)C(2) RNA in a c..
3. Franz-Ulrich,Hartl 德国 Max Planck Society 2011拉斯克奖;2011美国科学院院士 Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD
4. Adrian R. Krainer 美国 Cold Spring Harbor Laboratory 2019美国医学院院士;2020美国科学院院士;2021沃尔夫医学奖 Antisense Oligonucleotide Therapies for Neurodegenerative Diseases
5. Franz-Ulrich,Hartl 德国 Max Planck Society 2011拉斯克奖;2011美国科学院院士 In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment
6. Solomon H,Snyder 美国 Johns Hopkins University Medical School 1988美国医学院院士;1982沃尔夫医学奖;1980美国科学院院士 Mutant Huntingtin Disrupts the Nuclear Pore Complex
7. Joseph G,Gall 美国 Carnegie Institution of Washington 2006拉斯克奖;1972美国科学院院士 Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export
8. Franz-Ulrich,Hartl 德国 Max Planck Society 2011拉斯克奖;2011美国科学院院士 Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
9. Don W. Cleveland 美国 University of California, San Diego 2006美国科学院院士;2012美国医学院院士 Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzh..
10. Hyman, Bradley T. 美国 Harvard Medical School 2014美国医学院院士 Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzh..
11. Lee, Virginia Man-Yee 美国 University of Pennsylvania 2005美国医学院院士 LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
12. Nancy M. Bonini 美国 University of Pennsylvania 2012美国医学院院士;2012美国科学院院士 TDP-43 impairs sleep in Drosophila through Ataxin-2-dependent metabolic disturbance
13. Nancy M. Bonini 美国 University of Pennsylvania 2012美国医学院院士;2012美国科学院院士 m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration
14. Wolin, Sandra L. 美国 National Institutes of Health 2024美国科学院院士 CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF..
15. Samuel I. Stupp 美国 Northwestern University 2012美国工程院院士;2020美国科学院院士 CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF..
16. Roy Parker 美国 University of Colorado Boulder 2012美国科学院院士 Formation, function, and pathology of RNP granules
17. Wu, Joseph C. 美国 Stanford University School of Medicine 2019美国医学院院士 Death-seq identifies regulators of cell death and senolytic therapies
18. Rando, Thomas A. 美国 Stanford University School of Medicine 2016美国医学院院士 Death-seq identifies regulators of cell death and senolytic therapies
19. Orr, Harry T. 美国 University of Minnesota, Minneapolis 2014美国医学院院士 The PERK pathway: beneficial or detrimental for neurodegenerative diseases and tumor growth and canc..
20. De Strooper, Bart 英国 University College London 2022美国医学院院士 CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifie..