1. Departments of Molecular and Cellular Biology (Z.L., D.W.M., J.D.H.) and Biochemistry and Molecular Biophysics (S.-W.H., M.E., E.V., D.W.M., J.D.H.), University of Arizona, Tucson, Arizona 85721; and Department of Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030 (D.L.M.)