A Scaling Parameter for Predicting Pressure Wave Reflection in Stented Arteries

Abstract

A one-dimensional finite-difference model was developed to predict pressure wave reflections in stented arteries, and a parametric study of variations in stent and vessel properties was performed, including stent stiffness, length, and compliance transition region, as well as vessel radius and wall thickness. The model was solved using a combination of weighted essentially nonoscillatory and Runge–Kutta methods. Over 100 cases were tested and the magnitudes of the predicted waves were less than 0.5 mm Hg for all cases, less than 1% of the normal pulse pressure of 40 mm Hg. It was also shown that reasonable variations in these parameters could induce changes in reflection magnitude of up to ±50%. The relationship between each of these properties and the resulting wave reflection could be described in a simple manner, and the effect of all of them together could, in fact, be encompassed by a single nondimensional parameter titled “stent authority.” It is believed that stent authority is a novel way of relating the energy imposed upon the arterial wall by the stent to the fraction of the incident pressure energy that is reflected from the stented region. Based on these results, it is believed that stent design can have a significant effect on pressure wave reflections; however, it was concluded that their small magnitudes make clinical relevance of these waves unlikely, regardless of design.