Mycotic Abdominal Aortic Aneurysm Secondary to BCG Therapy for Non-muscle Invasive Urothelial Carcinoma of the Bladder

Author:

Godard Levi1ORCID,Lee Linda12,McGuinness Brandon1ORCID,Shirsat Hemlata3,Hoag Nathan12

Affiliation:

1. University of British Columbia, Island Medical Program, Victoria, BC, Canada

2. University of British Columbia, Dept. Of Urological Sciences, Victoria, BC, Canada

3. Dept. of Pathology, Victoria, BC, Canada

Abstract

Bacillus Calmette-Guerin (BCG) therapy for treatment of bladder cancer is a rare cause of Mycobacterium bovis infected aortic aneurysm. Typical presentations have included general malaise, fever, and lower back pain. We present a case with lower back pain and constipation as presenting symptoms, leading to diagnosis of mycotic aneurysm presumed secondary to intravesical BCG therapy. Treatment included open surgical repair with femoral vein grafting and anti-tubercular therapy. This case highlights the importance of a high index of suspicion for less common infectious complications of BCG therapy.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Surgery

Reference7 articles.

1. Bladder Cancer Canada. https://bladdercancercanada.org/en/bladder-cancer-facts/#:∼:text=HOW_COMMON_IS_IT,with_bladder_cancer_each_year. https://bladdercancercanada.org/en/bladder-cancer-facts/#:∼:text=HOW_COMMON_IS_IT,with_bladder_cancer_each_year. Accessed September 6, 2022.

2. Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with superficial bladder cancer? A meta-analysis of randomized trials

3. The mechanism of action of BCG therapy for bladder cancer—a current perspective

4. Systematische Übersichtsarbeit: aortale Komplikationen nach intravesikaler Bacillus Calmette-Guérin-Behandlung

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