Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

Author:

Bridgman Alanna C.1ORCID,Fitzmaurice Christina234ORCID,Dellavalle Robert P.567,Karimkhani Aksut Chante67,Grada Ayman8ORCID,Naghavi Mohsen2,Manafi Navid910,Olagunju Andrew T.1112,Olagunju Tinuke O.13,Somayaji Ranjani1415,Drucker Aaron M.1617

Affiliation:

1. School of Medicine, Queen’s University, Kingston, ON, Canada

2. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA

3. Division of Hematology, University of Washington, Seattle, WA, USA

4. Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, USA

5. School of Medicine, University of Colorado Denver, Aurora, CO, USA

6. Dermatology Service, US Department of Veterans Affairs (VA), Denver, CO, USA

7. Department of Dermatology, University of Colorado School of Medicine, Denver, CO

8. School of Medicine, Boston University, Boston, MA, USA

9. Ophthalmology Department, Iran University of Medical Sciences, Tehran, Iran

10. Ophthalmology Department, University of Manitoba, Winnipeg, MB, Canada

11. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada

12. Department of Psychiatry, University of Lagos, Lagos, Nigeria

13. Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada

14. Department of Medicine, University of Calgary, Calgary, AB, Canada

15. Department of Medicine, University of Washington, Seattle, WA, USA

16. Division of Dermatology, University of Toronto, Toronto, ON, Canada

17. Women’s College Research Institute, Women’s College Hospital, Toronto, ON, Canada

Abstract

Background Skin diseases can have high morbidity that can be costly to society and individuals. To date, there has been no comprehensive assessment of the burden of skin disease in Canada. Objectives To evaluate the burden of 18 skin and subcutaneous diseases from 1990 to 2017 in Canada using the Global Burden of Disease (GBD) data. Methods The 2017 GBD study measures health loss from 359 diseases and injuries in 195 countries; we evaluated trends in population health in Canada from 1990 to 2017 using incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs). Data are presented as rates (per 100 000), counts, or percent change with the uncertainty interval in brackets. Results From 1990 to 2017 for all skin diseases, DALY rates increased by 8% to 971 per 100 000 (674-1319), YLD rates increased by 8% to 897 per 100 000 (616-1235), YLL rates increased by 4% to 74 per 100 000 (53-89), and death rates increased by 18% to 5 per 100 000 (3-6). DALY rates for melanoma increased by 2% to 54 per 100 000 (39-68), for keratinocyte carcinoma by 14% to 17 per 100 000 (16-19), and for skin and subcutaneous disease by 8% to 900 per 100 000 (619-1233). The observed over expected ratios were higher for skin and subcutaneous disease (1.37) and keratinocyte carcinoma (1.17) and were lower for melanoma (0.73). Conclusions The burden of skin disease has increased in Canada since 1990. These results can be used to guide health policy regarding skin disease in Canada.

Funder

Bill and Melinda Gates Foundation

Publisher

SAGE Publications

Subject

Dermatology,Surgery

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