Enhanced discrete phase model for multiphase flow simulation of blood flow with high shear stress

Abstract

Shear stress is often present in the blood flow within blood-contacting devices, which is the leading cause of hemolysis. However, the simulation method for blood flow with shear stress is still not perfect, especially the multiphase flow model and experimental verification. In this regard, this study proposes an enhanced discrete phase model for multiphase flow simulation of blood flow with shear stress. This simulation is based on the discrete phase model (DPM). According to the multiphase flow characteristics of blood, a virtual mass force model and a pressure gradient influence model are added to the calculation of cell particle motion. In the experimental verification, nozzle models were designed to simulate the flow with shear stress, varying the degree of shear stress through different nozzle sizes. The microscopic flow was measured by the Particle Image Velocimetry (PIV) experimental method. The comparison of the turbulence models and the verification of the simulation accuracy were carried out based on the experimental results. The result demonstrates that the simulation effect of the SST k- ω model is better than other standard turbulence models. Accuracy analysis proves that the simulation results are accurate and can capture the movement of cell-level particles in the flow with shear stress. The results of the research are conducive to obtaining accurate and comprehensive analysis results in the equipment development phase.