Evaluating the Potential of Routine Blood Tests to Identify the Risk of Deep Vein Thrombosis: A 1-Year Monocenter Cohort Study

Author:

Signorelli Salvatore Santo1,Valerio Fiore1,Davide Castrogiovanni1,Oliveri Conti Gea2,Maria Fiore2,Ignazio Morana3,Margherita Ferrante2

Affiliation:

1. Medical Angiology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi Hospital, Catania, Italy

2. Department of Medical, Surgical Sciences and Advanced Technologies, G.F. Ingrassia, University of Catania, Catania, Italy

3. Division of Internal Medicine Critical Areas, Garibaldi Hospital, Catania, Italy

Abstract

Study on 295 consecutive medical patients to evaluate the potential of routine blood tests to identify the risk of deep vein thrombosis (DVT). The tests included in a DVT risk stratification model system were erythrocyte sedimentation rate, antithrombin III, C-reactive protein, D-dimer, and N-terminal pro-brain natriuretic peptide. The DVT risk stratification system was moderately prognostic (area under the curve: 0.838; 95% confidence interval: 0.771-0.904; P < .001), whereas its performance was as follows—sensitivity, 100%; specificity, 20%; positive predictive value, 21%; and negative predictive value, 100%. The prevalence of DVT and DVT + superficial thrombophlebitis was 7.5% and 3.1%, respectively. These routine blood tests may prove helpful to stratify the DVT risk in medical patients.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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