Floctafenine (IDARAC)—A New Analgesic: A Comparison with Placebo in Chronic Pain

Author:

Vickers M D1,Akbar F Ali2

Affiliation:

1. Consultant Anaesthetist and Consultant in Department of Clinical Investigation and Research, Dudley Road Hospital, Birmingham, England

2. Medical Division, Roussel Laboratories Ltd, Wembley Park, Middlesex, England

Abstract

A double-blind cross-over trial was conducted in 23 patients comparing the analgesic effect of floctafenine 200 mg with placebo, in chronic pain, each being given for a period of 1 week. There was statistically significant evidence that floctafenine was more effective than placebo in the relief of pain. Miscellaneous side-effects, none of a serious nature, were reported.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Reference5 articles.

1. Geisser S (1961) The Latin square as a repeated measurements design. In Proceedings of the fourth Berkeley Symposium on Mathematical Statistics and Probability. Neyman J (Ed). Vol 4, pp 241–250. University of California Press, Berkeley and Los Angeles.

2. The Two-Period Change-Over Design and Its Use in Clinical Trials

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