Genetic polymorphisms associated with heart failure: A literature review-Reference-Cited by-同舟云学术

Genetic polymorphisms associated with heart failure: A literature review

Published:2016-01-14 Issue:1 Volume:44 Page:15-29
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Guo Mengqi¹,Guo Guanlun²,Ji Xiaoping¹

Affiliation:

1. Key Laboratory of Cardiovascular Remodeling and Function Research, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, China

2. Hubei Key Laboratory of Advanced Technology of Automotive Components, School of Automotive Engineering, Wuhan University of Technology, Wuhan, China

Abstract

Objective To review possible associations reported between genetic variants and the risk, therapeutic response and prognosis of heart failure. Methods Electronic databases (PubMed, Web of Science and CNKI) were systematically searched for relevant papers, published between January 1995 and February 2015. Results Eighty-two articles covering 29 genes and 39 polymorphisms were identified. Conclusion Genetic association studies of heart failure have been highly controversial. There may be interaction or synergism of several genetic variants that together result in the ultimate pathological phenotype for heart failure.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0300060515604755

Reference117 articles.

1. Pathophysiological Characterization of Isolated Diastolic Heart Failure in Comparison to Systolic Heart Failure

2. Heart failure

3. Role of β adrenergic receptor polymorphisms in heart failure: Systematic review and meta-analysis

4. Association between Genetic Polymorphisms in the Renin-Angiotensin System and Systolic Heart Failure Revised by a Propensity Score-Based Analysis

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