Surface modification of pure titanium to improve its anti-inflammatory function

Author:

Sun Hanwen12,Zhang Yancong12,Dou Linbo3,Song Xinfeng12,Sun Chunyan1

Affiliation:

1. College of Medicine and Nursing, Dezhou University, PR China

2. Shandong Provincial Engineering Laboratory of New Pharmaceutical Excipients, Sustained and Controlled Release Technology, PR China

3. Dezhou People’s Hospital, PR China

Abstract

Objective: Surface-modified titanium material was prepared to explore its corrosion resistance and microbial adhesion. Methods: Atmospheric pressure plasma was used to modify the surface of pure titanium. The surface morphology and adhesion morphology of P. gingivalis (Porphyromonas gingivalis) were observed through morphology scanning electron microscopy. Reactive oxygen species (ROS) formation was detected using a fluorescence spectrophotometer. Electrochemical corrosion properties of the material were detected using simulated fluids and SAGF artificial saliva as electrolyte. Bacteria suspension absorbance was tested using an enzyme standard. Results: After plasma modification, the material surface exhibited numerous ROS formations and improved wettability. Compared with the control group, corrosion potential was higher but corrosion current was lower in simulated body fluids and artificial saliva. Bacterial-suspension absorbance was significantly lower than that in the control group on days 3 and 5 ( P <0.05). Conclusion: The electrochemical and microbial corrosion performance of titanium can be improved by atmospheric pressure plasma. Therefore, this method can thus be used for the surface modification of oral and bone implant materials.

Publisher

SAGE Publications

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