Indole-3-carbinol induces apoptosis of chronic myelogenous leukemia cells through suppression of STAT5 and Akt signaling pathways
Author:
Affiliation:
1. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran
2. Department of Hematology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
Publisher
IOS Press
Subject
General Medicine
Link
http://journals.sagepub.com/doi/pdf/10.1177/1010428317705768
Reference49 articles.
1. New Insights into the Pathophysiology of Chronic Myeloid Leukemia and Imatinib Resistance
2. The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells
3. Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
4. Stat5 is indispensable for the maintenance of bcr/abl ‐positive leukaemia
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