Recent Advances in Natural Products with Anti-Leukemia and Anti-Lymphoma Activities

Author:

Sun Zhi-Gang1,Yao Cheng-Jie2,Ullah Inam3,Hailiang Zhu3

Affiliation:

1. Linyi Central Hospital Central Laboratory Linyi China

2. Yishui Juncheng Sika Deer Wildlife Research Institute Yishui Juncheng Sika Deer Wildlife Research Institute Linyi China

3. Nanjing University State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing China

Abstract

Abstract: Leukemia and lymphoma are the most common blood cancers, which pose a critical threat to the health of adults and children. The total incidence and mortality rates of both are approximately 6% globally. Compared with the expensive cost of CAR T cell therapy, natural products from animals, plants and microorganisms have the characteristics of wide-range sources and costeffectiveness in the treatment of cancer. Moreover, the drug resistance that emerged in leukemia and lymphoma treatments shows an urgent need for new drugs. However, in addition to the natural products that have been marketed in the treatment of leukemia and lymphoma, there have been a large number of studies on natural products that fight blood cancer in recent years. This review summarized the recent studies on natural compounds with anti-lymphoma and anti-leukemia activities, hoping to provide novel weapons into the drug development arsenal.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology,General Medicine

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