Varicella zoster virus cerebral aneurysmal vasculopathy presenting in a newly-diagnosed HIV-positive patient

Author:

Tomkins Andrew1ORCID,Babu Chitra1,Herwadkar Amit2,Siripurapu Rekha2,McKee David34

Affiliation:

1. The Hathersage Centre, The Northern Contraception, Sexual Health and HIV Service, Manchester University Foundation Trust, Manchester, UK

2. Department of Radiology, Salford Royal NHS Foundation Trust, Salford, UK

3. Department of Neurology, Salford Royal NHS Foundation Trust, Salford, UK

4. Department of Neurology, Manchester University Foundation Trust, Manchester, UK

Abstract

We report the case of a newly-diagnosed HIV-positive patient with varicella zoster virus aneurysmal vasculopathy confirmed on intrathecal antibody testing, despite a negative Cerebrospinal fluid (CSF) Varicella Zoster Virus (VZV) Polymerase Chain Reaction (PCR). This highlights the importance of prompt treatment with antiviral and steroid therapy in the presence of clinical or radiological suspicion whilst awaiting further confirmatory testing.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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