Bilateral Dentate Gyrus Structural Alterations in a Cat Associated With Hippocampal Sclerosis and Intraventricular Meningioma

Author:

Klang A.1,Thaller D.1,Schmidt P.1,Kovacs G. G.2,Halasz P.3,Pakozdy A.4

Affiliation:

1. Institute of Pathology and Forensic Veterinary Medicine, Department for Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria

2. Institute of Neurology, Medical University of Vienna, Vienna, Austria

3. National Institute of Neuroscience, Budapest, Hungary

4. University Clinic for Small Animals, Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria

Abstract

A 13-year-old cat had a history of seizures for 3 years that resembled temporal lobe epilepsy. Histologic examination of the brain revealed bilateral hippocampal alterations, including hypergyration and broadening of the dentate gyrus associated with hippocampal sclerosis and an intraventricular meningioma near the hippocampal region. The findings in the dentate gyrus were interpreted as a congenital malformation; however, it could not be ruled out that the alterations were induced by the seizures. Similar changes of the dentate gyrus have not been previously described in cats.

Publisher

SAGE Publications

Subject

General Veterinary

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1. A review of primary central nervous system neoplasms of cats;Veterinary Pathology;2023-02-20

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4. Magnetresonanztomographische Befunde bei 143 Katzen mit Epilepsie;Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere;2022-02

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