4.3 In-vitro genotoxicity tests to detect carcinogenicity: a systematic review
Author:
Affiliation:
1. Toxicology Project Leader, Non-Clinical Safety, F. Hoffmann La Roche, 4070 Basel, Switzerland.
Publisher
SAGE Publications
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://journals.sagepub.com/doi/pdf/10.1177/0960327109105770
Reference11 articles.
1. Prediction of Chemical Carcinogenicity in Rodents from in Vitro Genetic Toxicity Assays
2. Predicting Rodent Carcinogenicity from Four in vitro Genetic Toxicity Assays: An Evaluation of 114 Chemicals Studied by the National Toxicology Program
3. Interpretation of the biological relevance of genotoxicity test results: the importance of thresholds
4. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop
5. Human biological relevance and the use of threshold-arguments in regulatory genotoxicity assessment: experience with pharmaceuticals
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