Fatal Paracetamol Poisoning in an Epileptic

Author:

Minton N.A.1,Henry J.A.1,Frankel R.J.2

Affiliation:

1. Poisons Unit, Guy's Hospital, London SE1 9RT

2. Frimley Park Hospital, Portsmouth Road, Frimley, Surrey GU16 5UJ, UK

Abstract

Treatment nomograms are used in paracetamol poisoning for indicating when antidotes should be given to prevent hepatic or renal damage.1 We report a fatal case of paracetamol poisoning in an epileptic taking phenytoin, in whom no antidotal treatment was given because it was not indicated.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology

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2. The Risk of Drug-Drug Interactions with Paracetamol in a Population of Hospitalized Geriatric Patients;Journal of Pharmaceutics;2020-01-20

3. PharmGKB summary;Pharmacogenetics and Genomics;2015-08

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5. Acetaminophen;Drug-Induced Liver Disease;2013

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