Pharmacokinetics and Pharmacodynamics of Peldesine (BCX-34), a Purine Nucleoside Phosphorylase Inhibitor, following Single and Multiple Oral Doses in Healthy Volunteers-Reference-Cited by-同舟云学术

Pharmacokinetics and Pharmacodynamics of Peldesine (BCX-34), a Purine Nucleoside Phosphorylase Inhibitor, following Single and Multiple Oral Doses in Healthy Volunteers

Published:2000-04 Issue:4 Volume:40 Page:410-420
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:

Author:

Viegas Tacey X.,Omura George A.,Stoltz Randall R.,Kisicki James

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference12 articles.

1. Purine nucleoside phosphorylase deficiency;Markert;Immunodeficiency.,1991

2. Purine nucleoside phosphorylase deficiency;Osborne;J Clin Invest.,1977

3. Safety, pharmacokinetics and pharmacodynamics of CI-1000, a purine nucleoside phosphorylase inhibitor in healthy volunteers (abstract);Hounslow;Clin Pharmacol Therapeutics.,1997

4. In vivo and in vitro pharmacologic activity of the purine nucleoside phosphorylase inhibitor BCX-34: the role of GTP and dGTP;Bantia;Immunopharmacology.,1996

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