Pharmacokinetics and Safety of Z‐321, a Novel Specific Orally Active Prolyl Endopeptidase Inhibitor, in Healthy Male Volunteers
Author:
Affiliation:
1. Department of Pharmacology
2. Clinical Pharmacology, Hamamatsu University School of Medicine, Hamamatsu, Japan
3. Zeria Pharmaceutical Company, Tokyo, Japan
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1177/009127009903900505
Reference20 articles.
1. New Potent Prolyl Endopeptidase Inhibitors: Synthesis and Structure-Activity Relationships of Indan and Tetralin Derivatives and Their Analogs
2. Vasopressin in Alzheimer's disease: A study of postmortem brain concentrations
3. Reduction of arginine-vasopressin in the cerebral cortex in Alzheimer type senile dementia.
4. Deficiency of kallikrein-like enzyme activities in cerebral tissue of patients with alzheimer's disease
5. Increase in the septal vasopressin content by prolyl endopeptidase inhibitors in rats
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