Health-related quality of life on combination therapy with peritoneal dialysis and hemodialysis in comparison with hemodialysis and peritoneal dialysis: A cross-sectional study

Author:

Tanaka Mototsugu1,Ishibashi Yoshitaka2,Hamasaki Yoshifumi1,Kamijo Yuka2,Idei Mayumi3,Kawahara Takuya4,Nishi Takahiro5,Takeda Michio6,Nonaka Hiroshi78,Nangaku Masaomi1,Mise Naobumi9

Affiliation:

1. Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Japan

2. Division of Nephrology, Department of Medicine, Japanese Red Cross Medical Center, Tokyo, Japan

3. Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

4. Clinical Research Support Center, The University of Tokyo Hospital, Japan

5. Nishi Clinic, Tokyo, Japan

6. Akihabara Izumi Clinic, Tokyo, Japan

7. Nonaka Clinic, Tokyo, Japan

8. Deceased.

9. Division of Nephrology, Department of Medicine, Mitsui Memorial Hospital, Tokyo, Japan

Abstract

Background:The health-related quality of life (HRQOL) of dialysis patients has not been well examined, especially in combination therapy with peritoneal dialysis and hemodialysis (PD+HD) patients. We compared the HRQOL of PD+HD patients with that of HD and PD patients.Methods:A multicenter, cross-sectional study was conducted on 36 PD+HD, 103 HD, and 90 PD patients in Japan who completed the Kidney Disease Quality of Life Short Form 36, version 1.3. HRQOL scores were summarized into physical- (PCS), mental- (MCS), role/social- (RCS), and kidney disease component summaries (KDCS).Results:Of the PD+HD patients, 31 (86%) transferred from PD and 5 (14%) transferred from HD. They had the longest dialysis vintage and the smallest urine volume. PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients. However, the RCS score for PD+HD was significantly higher than that for HD ( p = 0.020) and comparable with that for PD. PD+HD and PD were associated with significantly higher RCS scores than HD after adjusting for age, gender, diabetic nephropathy, dialysis vintage, ischemic heart disease, and peripheral arterial disease.Conclusions:For RCS, HRQOL in PD+HD patients was better than that in HD and comparable with that in PD patients, whereas the PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients.

Publisher

SAGE Publications

Subject

Nephrology,General Medicine

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