Morphometric analysis of alpha-1, 3-galactosyltransferase knockout pig kidney and heart

Author:

Vasamsetti Bala Murali Krishna1,Park Sang Hyoun1,Rallabandi Harikrishna Reddy1,Lee Heasun1,Byun Sung-June1,Ock Sun A1,Lee Hwi-Cheul1,Hwang Seongsoo1,Oh Keon Bong1ORCID

Affiliation:

1. Animal Biotechnology Division, National Institute of Animal Science, Republic of Korea

Abstract

We report a morphometric evaluation of α1,3-galactosyltransferase knockout (GTKO) pig heart and kidney ( n = 9) at the end of one, three and seven months. Organs parameters gradually increased with the age ( p < 0.05) and body weight ( p < 0.05) of the pigs. Organs morphometries were significantly correlated to the age and body weight of the animal. We were able to conclude the average size of GTKO pig heart and kidney based on age and body weight, which could be helpful in estimating the size of these organs non-invasively for transplantation.

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

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