Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft-Reference-Cited by-同舟云学术

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

Published:2016-04-05 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Mohiuddin Muhammad M.,Singh Avneesh K.,Corcoran Philip C.,Thomas III Marvin L.,Clark Tannia,Lewis Billeta G.,Hoyt Robert F.,Eckhaus Michael,Pierson III Richard N.,Belli Aaron J.,Wolf Eckhard,Klymiuk Nikolai,Phelps Carol,Reimann Keith A.,Ayares David,Horvath Keith A.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms11138.pdf

Reference31 articles.

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2. Bach, F. H., Winkler, H., Ferran, C., Hancock, W. W. & Robson, S. C. Delayed xenograft rejection. Immunol.Today 17, 379–384 (1996).

3. Byrne, G. W. et al. Increased immunosuppression, not anticoagulation, extends cardiac xenograft survival. Transplantation 82, 1787–1791 (2006).

4. Kuwaki, K. et al. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat. Med. 11, 29–31 (2005).

5. Mohiuddin, M. M. et al. B-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months. Am. J. Transplant. 12, 763–771 (2012).

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