Statistical Considerations on the Evaluation of Imbalances of Adverse Events in Randomized Clinical Trials

Author:

Ma Haijun,Ke Chunlei,Jiang Qi,Snapinn Steven

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Public Health, Environmental and Occupational Health,Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference24 articles.

1. Council for International Organizations of Medical Sciences. Management of Safety Information from Clinical Trials. Geneva, Switzerland: Council for International Organizations of Medical Sciences; 2005.

2. Crowe BJ, Xia HA, Berlin JA, et al. Recommendations for safety planning, data collection, evaluation and reporting during drug, biologic and vaccine development: a report of the safety planning, evaluation, and reporting team. Clinical Trials. 2009;6(5):430–440.

3. Talbot J, Aronson JK. Stephens’ Detection and Evaluation of Adverse Drug Reactions Principles and Practices. 6th ed. New York, NY: John Wiley & Sons Ltd; 2012.

4. Jiang Q, Xia HA. Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting. New York, NY: Taylor & Francis; 2015.

5. Food and Drug Administration. Guidance for Industry and Investigators, Safety Reporting Requirements for INDs and BA/BE Studies. Silver Spring, MD: Food and Drug Administration; 2012.

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