Psychosocial Features of Neurofibromatosis Type 1 in Children and Adolescents

Abstract

Neurofibromatosis type 1 (NF1) is a common neurologic condition associated with a wide variety of developmental deficits that have an important impact on children and adolescents. Objective: This article aims to document the psychosocial features of NF1 and to report the interventions described to address the needs of pediatric patients with NF1. Methods: A literature review was conducted concerning the social life, mental health, and quality of life (QOL) of children and adolescents with NF1 as well as the psychosocial interventions addressed to this population. Results: Compared to unaffected children and adolescents of the general population, pediatric patients with NF1 have an increased risk of having social difficulties, mental health disorders, behavioral and emotional problems, as well as diminished QOL. Only 3 articles describe interventions within the NF1 population to address these difficulties. Conclusion: There is a need to develop and assess psychosocial interventions for patients with NF1.