Quantitative Techniques in Neuropathology-Reference-Cited by-同舟云学术

Quantitative Techniques in Neuropathology

Published:1990-01 Issue:1_part_2 Volume:18 Page:105-114
ISSN:0192-6233
Container-title:Toxicologic Pathology
language:en
Short-container-title:Toxicol Pathol

Author:

Broxup Brian R.¹,Yipchuck George¹,McMillan Ian²,Losos George J.¹

Affiliation:

1. Division of Pathology. Bio-Research Laboratories Ltd., 87 Senneville Road, Senneville, Quebec, Canada H9X 3R3

2. Department of Animal and Poultry Science, University of Guelph, Guclph, Ontario, Canada NIG 2W1

Abstract

In the future, quantitative techniques will probably be used in industry as part of Tier II studies for the evaluation of chemicals and drugs for their neurotoxic potential. Movement towards quantifying some structures or neuropathological changes will be made possible by advances in tissue preparation and computer technology. Emphasis will need to be placed on standardized techniques, good quality samples and sampling techniques in order to produce good quantitative data in a reasonable time. In this paper, different sampling techniques are evaluated using a cross section of rat sural nerve as the tissue for quantitative investigation.

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/019262339001800116

Reference28 articles.

1. Quantitation in Neuropathology

2. Schmidt-Lanterman clefts: A morphometric study in human sural nerve

3. Unmyelinated axon subpopulations in the rat peripheral nervous system

4. Morphometric evaluation of degenerative and regenerative changes in isoniazid-induced neuropathy

5. Morphometry in Pathology: Another Look at Diagnostic Histopathology

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