1. Post Graduate Program in Medicine, Medical Sciences, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, Porto Alegre, Brazil
2. Post Graduate Program in Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, Porto Alegre, Brazil
3. Health Department of the State of Rio Grande do Sul, Porto Alegre, Brazil
4. Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Rua Ramiro Barcelos, Porto Alegre, Brazil
5. Department of Genetics, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, Porto Alegre, Brazil