The Effect of Infant Formulas With 4 or 8 g/L GOS/FOS on Growth, Gastrointestinal Symptoms, and Behavioral Patterns: A Prospective Cohort Study

Author:

Tonon Karina Merini1ORCID,Tomé Thaís Moreno2ORCID,Mosquera Elaine Martins Bento2,Perina Natália Pratis2,Lazarini Tamara2

Affiliation:

1. Independent Researcher, Florianópolis, Santa Catarina, Brazil

2. Nestlé Brazil LTDA, Sao Paulo, São Paulo, Brazil

Abstract

There is a lack of studies investigating the clinical benefits of prebiotic-supplemented infant formula. In this study, healthy infants that started, on medical recommendation, artificial feeding with one of 2 infant formulas containing 4 g/L of GOS/FOS (9:1) (IF4 group; n = 60) or 8 g/L of GOS/FOS (9:1) (IF8 group; n = 60) were followed for 30 days to the evaluation of growth and gastrointestinal symptoms. Exclusively breastfed infants (EBF; n = 60) were followed up as a reference. Both infant formulas supported adequate weight gain, however, IF4 formula promotes growth more similar to breastfed infants. There was no additional benefit of a dose higher than 4 g/L of GOS/FOS on gastrointestinal symptoms.

Funder

Nestlé Brazil LTDA

Publisher

SAGE Publications

Subject

Pediatrics,Pediatrics, Perinatology, and Child Health

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