Review : Grand Rounds from International Lupus Centres Accelerated atherosclerosis and coronary disease in SLE

Author:

Farhey Y.1,Hess E.V.1

Affiliation:

1. Division of Immunology, Department of Internal Medicine, University of Cincinnati College of Medicine; 231 Bethesda Avenue, Cincinnati, Ohio 45267-0563, USA

Abstract

Atherosclerosis may represent a significant cause of death and morbidity in patients with systemic lupus erythematosus. Coronary involvement is more premature in lupus patients. We present the case of a young woman diagnosed with SLE at the age of 20 years who had a myocardial infarction at age 29 years. We review the mechanisms of atherosclerosis, the interrelations between atherosclerosis and autoimmunity, and between atherosclerosis and SLE. We also review the risk factors, influence of disease and treatment and the guidelines for management of accelerated atherosclerosis in lupus patients.

Publisher

SAGE Publications

Subject

Rheumatology

Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Renal Involvement in Children with Systemic Lupus Erythematosus;Pediatric Nephrology;2015-11-12

2. References;The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae;2015

3. Origin of Typical Disease Sequelae;The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae;2015

4. Renal Involvement in Children with Systemic Lupus Erythematosus;Pediatric Nephrology;2015

5. Matrix metalloproteinase 9 polymorphisms and systemic lupus erythematosus: correlation with systemic inflammatory markers and oxidative stress;Lupus;2014-11-21

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