Clinical Diagnosis of Cardiac Involvement in Systemic Lupus Erythematosus

Author:

KONG THOMAS Q.1,KELLUM ROBERT E.1,HASERICK JOHN R.1

Affiliation:

1. From the Department of Cardiovascular Disease, and the Department of Dermatology, The Cleveland Clinic Foundation, Cleveland, Ohio.

Abstract

A review was made of the case histories and autopsy reports of 30 patients with systemic lupus erythematosus who had clinical cardiovascular involvement. The presence of an enlarged heart or of gallop rhythm strongly suggests myocardial involvement, but the electrocardiogram is not specific. Signs and symptoms referable to the heart are unusual as a first manifestation of systemic lupus erythematosus, and in patients receiving suppressive chemotherapy they do not further worsen the prognosis. Systolic murmurs cannot be interpreted as conclusive evidence of Libman-Sacks valvulitis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference7 articles.

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3. GRoss L.: The heart in atypical verrucous endocarditis (Libman-Sacks). Contributions to the Medical Sciences in Honor of Dr. Emanuel Libman by His Pupils Frienids and Colleagues. Vol. 2. New York The International Press 1932 p. 527.

4. The cardiac lesions in Libman-Sacks disease; with a consideration of its relationnship to acute diffuse Iupus erythematosus;GR;Am. J. Path.,1940

5. DISSEMINATED LUPUS ERYTHEMATOSUS

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