Safety Assessment of PEGylated Oils as Used in Cosmetics

Author:

Burnett Christina L.1,Heldreth Bart2,Bergfeld Wilma F.3,Belsito Donald V.3,Hill Ronald A.3,Klaassen Curtis D.3,Liebler Daniel C.3,Marks James G.3,Shank Ronald C.3,Slaga Thomas J.3,Snyder Paul W.3,Andersen F. Alan4

Affiliation:

1. Cosmetic Ingredient Review Scientific Analyst/Writer, Washington, DC, USA

2. Cosmetic Ingredient Review Chemist, Washington, DC, USA

3. Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA

4. Former Director, Cosmetic Ingredient Review, Washington, DC, USA

Abstract

PEGylated oil is a terminology used to describe cosmetic ingredients that are the etherification and esterification products of glycerides and fatty acids with ethylene oxide. The Cosmetic Ingredient Review Expert Panel (Panel) considered the safety of PEGylated oils, which function primarily as surfactants in cosmetic products. The Panel reviewed relevant animal and human data provided in this safety assessment and concluded that the 130 chemically related PEGylated oils were safe as cosmetic ingredients in the present practices of use and concentration when formulated to be nonirritating.

Publisher

SAGE Publications

Subject

Toxicology

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