Amended Safety Assessment of Hypericum Perforatum-Derived Ingredients as Used in Cosmetics

Author:

Becker Lillian C.1,Bergfeld Wilma F.2,Belsito Donald V.2,Hill Ronald A.2,Klaassen Curtis D.2,Liebler Daniel C.2,Marks James G.2,Shank Ronald C.2,Slaga Thomas J.2,Snyder Paul W.2,Andersen F. Alan3

Affiliation:

1. Cosmetic Ingredient Review Scientific Analyst/Writer, Washington, DC, USA

2. Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA

3. Former Director, Cosmetic Ingredient Review, Washington, DC, USA

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) has issued an amended safety assessment of 7 Hypericum perforatum-derived ingredients as used in cosmetics. A common name for this plant is St John wort. These ingredients function in cosmetics as skin-conditioning agents—miscellaneous and antimicrobial agents. The Panel reviewed relevant animal and human data related to the H perforatum-derived ingredients. Because formulators may use more than 1 botanical ingredient in a formulation, caution was urged to avoid levels of toxicological concern for constituent chemicals and impurities. The Panel concluded that H perforatum-derived ingredients were safe as cosmetic ingredients in the practices of use and concentration as described in this safety assessment.

Publisher

SAGE Publications

Subject

Toxicology

Reference81 articles.

1. Final report on the safety assessment of Hypericum perforatum extract and Hypericum perforatum oil. Int J Toxicol. 2001;20(suppl 2):31–39.

2. CIR Science and Support Committee of the Personal Care Products Council. Hypercium perforatum-derived ingredients. Unpublished data submitted by Personal Care Products Council; 2012:12 p.

3. Pharmakognosie — Phytopharmazie

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