Radiographic and Clinical Evidence for Osteoarthritis at Medium-Term Follow-up after Arthroscopic Partial Medial Meniscectomy

Author:

Lamplot Joseph D.1,Tompkins William P.1,Friedman Michael V.2,Nguyen Joseph T.3,Rai Muhammad Farooq14ORCID,Brophy Robert H.1ORCID

Affiliation:

1. Department of Orthopaedic Surgery, School of Medicine, Washington University, St. Louis, MO, USA

2. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA

3. Hospital for Special Surgery, New York, NY, USA

4. Department of Cell Biology & Physiology, Washington University School of Medicine, St. Louis, MO, USA

Abstract

Objective The purpose of this study is to assess if incident radiographic osteoarthritis (OA) is associated with clinical OA symptoms at midterm follow-up after arthroscopic partial medial meniscectomy (APMM). Design A total of 44 patients (43% females, mean age 50.1 ± 2.8 years, minimum 5.6-year follow-up) with isolated medial meniscal tears and no-to-mild preoperative radiographic OA underwent APMM. Incident radiographic OA was assessed using the modified Kellgren-Lawrence (K-L) classification. Patients completed the Knee Injury and Osteoarthritis Outcomes Score (KOOS), and subscale thresholds for assessment of a symptomatic knee (KOOS OA criteria) and for Patient non-Acceptable Symptom State (PASS-N) following anterior cruciate ligament reconstruction (ACL-R) were calculated. Results Incident medial compartment OA occurred in 50% of patients. Morbidly obese patients (body mass index ≥35 kg/m2) were more likely to demonstrate incident radiographic OA (100% vs. 41%, P = 0.002). Forty-three percent of patients met KOOS OA criteria, while 77% were PASS-N. Females were more likely to meet KOOS OA criteria (73% vs. 21%, P = 0.009). Patients with incident radiographic OA in any compartment were more likely than those without radiographic OA to meet KOOS OA criteria (71% vs. 17%, P = 0.008). Patients with preoperative K-L grade 2 changes in any compartment were more likely to meet KOOS OA criteria than those without K-L grade 2 changes in any compartment (83% vs. 35%, P = 0.037). Conclusions Roughly half of APMM patients will have incident radiographic OA within 6 years of APMM, and this risk increases with obesity. Females and patients with incident radiographic OA are more likely to meet clinical thresholds for OA.

Funder

Orthopaedic Research and Education Foundation (OREF) Resident Clinician Scientist Training Grant

Publisher

SAGE Publications

Subject

Physical Therapy, Sports Therapy and Rehabilitation,Biomedical Engineering,Immunology and Allergy

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