Current and future treatment options for cystic fibrosis lung disease: latest evidence and clinical implications-Reference-Cited by-同舟云学术

Current and future treatment options for cystic fibrosis lung disease: latest evidence and clinical implications

Published:2016-05 Issue:3 Volume:7 Page:170-183
ISSN:2040-6223
Container-title:Therapeutic Advances in Chronic Disease
language:en
Short-container-title:Therapeutic Advances in Chronic Disease

Author:

Edmondson Claire¹,Davies Jane C.²

Affiliation:

1. Royal Brompton & Harefield NHS Foundation Trust, Paediatric Respiratory Medicine, London, UK

2. Imperial College London, Paediatric Respirology and Experimental Medicine, London SW7 2AZ, UK

Abstract

Treatment for cystic fibrosis (CF) has conventionally targeted downstream consequences of the defect such as mucus plugging and infection. More recently, significant advances have been made in treating the root cause of the disease, namely a defective CF transmembrane conductance regulator (CFTR) gene. This review summarizes current pulmonary treatment options and highlights advances in research and development of new therapies.

Publisher

SAGE Publications

Subject

Medicine (miscellaneous)

Link

http://journals.sagepub.com/doi/pdf/10.1177/2040622316641352

Reference85 articles.

1. Denufosol Tetrasodium in Patients with Cystic Fibrosis and Normal to Mildly Impaired Lung Function

2. Long-Term Inhaled Dry Powder Mannitol in Cystic Fibrosis

3. Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

4. The effect of dornase alfa on ventilation inhomogeneity in patients with cystic fibrosis

5. Gene therapy in cystic fibrosis

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Symptoms, burden, and unmet needs of patients living with exocrine pancreatic insufficiency: a narrative review of the patient experience;BMC Gastroenterology;2024-03-14

2. Decatastrophizing research irreproducibility;Biochemical Pharmacology;2024-02

3. Genomic newborn screening for rare diseases;Nature Reviews Genetics;2023-06-29

4. Therapeutic interventions alter ecological interactions among cystic fibrosis airway microbiota;Frontiers in Microbiology;2023-05-30

5. Nanomedicine Applied to Inflammatory and Infectious Pulmonary Diseases;Interdisciplinary Biotechnological Advances;2023