Triterpenoid Saponins From the Stem Bark of Pentaclethra eetveldeana

Author:

Pertuit David1,Kapundu Mpuza2,Mitaine-Offer Anne-Claire1,Miyamoto Tomofumi3,Tanaka Chiaki3,Delaude Clément4,Lacaille-Dubois Marie-Aleth1

Affiliation:

1. Laboratoire de Pharmacognosie, PEPITE EA 4267, UFR des Sciences de Santé, Université de Bourgogne Franche-Comté, Dijon Cedex, France

2. Centre d’études des Substances Naturelles d’Origine Végétale, Faculté des Sciences Pharmaceutiques, Université de Kinshasa, République Démocratique du Congo

3. Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan

4. Centre de Recherche Phytochimique, Université de Liège, Institut de Chimie B-6, Liège, Belgium

Abstract

Two previously undescribed triterpenoid saponins together with 4 known ones were isolated from the stem bark of Pentaclethra eetveldeana De Wild. & Th. Dur. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments in combination with mass spectrometry as 3- O-β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyloleanolic acid and 3- O-β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosylhederagenin.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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