A New Cytotoxic Tirucallane from the Twigs of Walsura trichostemon

Author:

Sichaem Jirapast1,Siripong Pongpun2,Tip-pyang Santi1,Phaopongthai Jatuporn3

Affiliation:

1. Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand

2. Natural Products Research Section, Research Division, National Cancer Institute, Bangkok, 10400, Thailand

3. Department of Chemistry, Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi, PathumThani 12110, Thailand

Abstract

A new tirucallane, trichostemonol (1), together with five known compounds (2–6) were isolated from the twigs of Walsura trichostemon. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cells.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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