Apowalsogynes A and B, Two Highly Oxidized 3,4-Seco-Apotirucallane Triterpenoids from Walsura chrysogyne-Reference-Cited by-同舟云学术

Apowalsogynes A and B, Two Highly Oxidized 3,4-Seco-Apotirucallane Triterpenoids from Walsura chrysogyne

Published:2017-08 Issue:8 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Nugroho Alfarius Eko¹,Okuda Maho¹,Yamamoto Yukari¹,Chin-Piow Wong¹,Hirasawa Yusuke¹,Kaneda Toshio¹,Shirota Osamu²,Hadi A. Hamid A.³,Morita Hiroshi¹

Affiliation:

1. Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo 142-8501, Japan

2. Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, 1314-1 Shido, Sanuki City, Kagawa 769-2193, Japan

3. Department of Chemistry, Faculty of Science, University Malaya, 50603 Kuala Lumpur, Malaysia

Abstract

Two new 3,4- seco-apotirucallane triterpenoids, Apowalsogynes A and B (1 and 2), were isolated from the barks of Walsura chrysogyne, and their structures were determined on the basis of the NMR and CD spectra, and by using the modified Mosher's method. In addition, the cytotoxic activities of 1 and 2 against various cancer cell lines were evaluated.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200810

Reference18 articles.

1. (20S*,24S*)-25-Hydroxy-20,24-epoxy-A-homo-4-oxadammaran-3-one (Chrysura) isolated from the leaves ofWalsura chrysogyne

2. Ceramicine A and walsogyne A, novel limonoids from two species of Meliaceae

3. The First Limonoid Peroxide in the Meliaceae Family: Walsuronoid A from Walsura robusta

4. Novel apo-tirucallane triterpenoids from Walsura trifoliata

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