Chemical Composition, Antioxidant and Anticholinesterase Activities of Gentianella azurea from Russian Federation

Author:

Olennikov Daniil N.1,Chirikova Nadezhda K.2,Vennos Cecile3

Affiliation:

1. Laboratory of Medical and Biological Research, PlaMeta Group, Institute of General and Experimental Biology, Siberian Division of Russian Academy of Science, 6 Sakh'yanovoy Str., Ulan-Ude, Russian Federation 670047

2. Department of Biochemistry and Biotechnology, North-Eastern Federal University, 58 Belinsky Str., Yakutsk, 677027, Russian Federation

3. Regulatory and Medical Scientific Affairs, Padma AG, 1 Underfeldstrasse, Hinwil, CH-8340, Switzerland

Abstract

Phytochemical study of Gentianella azurea (Bunge) Holub (Gentianaceae) collected in Buryatia Republic (Russian Federation) resulted in the isolation of twenty-one compounds including bellidifolin, bellidin, isobellidifolin, norswertianolin, isobellidifolin-8- O-β-D-glucopyranoside, orientin, cynaroside, cosmosiin, apigenin, 4′- O-caffeoylswertiamarin, swertiamarin-6′- O-β-D-glucopyranoside and sweroside, firstly detected in this species. The extracts and individual compounds were shown to possess antioxidant and anticholinesterase potential.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference16 articles.

1. AseevaTA, DashievDB, DashievAD, NikolaevSM, SurkovaNA, ChekhirovaGV, YurinaTA. (2008) Tibetan Medicine of Buryats. SO RAN, Novosibirsk. 217–264. (in Russian).

2. Isolation and Structure Elucidation of Two New Xanthones from Gentiana azurium Bunge (Fam. Gentianaceae)

3. Chemical Investigation of Anagallidium dichotomum and Anticholinesterase Activity of Its Constituents

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