A New Cembrane, from Soft Coral Genus Sarcophyton in Borneo-Reference-Cited by-同舟云学术

A New Cembrane, from Soft Coral Genus Sarcophyton in Borneo

Published:2018-02 Issue:2 Volume:13 Page:1934578X1801300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Kamada Takashi¹,Zanil Intan Irna¹,Phan Chin-Soon¹,Vairappan Charles Santhanaraju

Affiliation:

1. Laboratory of Natural Products Chemistry, Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah, 88400 Kota Kinabalu, Sabah, Malaysia

Abstract

One new cembrane diterpene, (1 S, 2 E, 4 R, 6 E, 8 S, 11 S, 12 S)-11,12-epoxy-8-hydroperoxy-4-hydroxy-2,6-cembradiene (1) was isolated from a population of Bornean soft coral genus Sarcophyton collected from the coastal waters Bohey Dulang, Sabah, Malaysia. Its structure was elucidated based on extensive spectroscopic analysis including NMR and HRESIMS spectra. Cytotoxic, anti-inflammatory and antibacterial activities were tested.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801300203

Reference12 articles.

1. Anti-Inflammatory Activities of Natural Products Isolated from Soft Corals of Taiwan between 2008 and 2012

2. Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans

3. Cytotoxic Cembranoids from the Red Sea Soft Coral Sarcophyton glaucum

4. Chemopreventive Effect of Sarcophine-diol on NOR-1-Induced TPA-Promoted Skin Carcinogenesis in Female HOS:HR-1 Mice

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